【摘要】 目的调查早产儿住院期间医院感染的发生情况,探讨其危险因素,为改进医院感染的监控与干预措施提供依据。方法对1992年1月-2004年12月,在医院新生儿重症监护病房住院的1026例早产儿及其医院感染病例进行分析和总结。结果1026例早产儿中共266例发生316例次医院感染,发生率为25.9%;早产儿发生医院感染的危险性相关因素为肠外营养、出生体重≤1500 g、呼吸机治疗(P<0.01);感染部位以肺炎占首位(46.8%);医院感染病死率为3.8%。结论充分了解早产儿发生医院感染的高危因素、缩短肠外营养的时间、加强对侵入性治疗装置的监护和护理、及时撤除有创操作及治疗,将有助于减少早产儿医院感染的发生。更多还原

【Abstract】 OBJECTIVE To investigate the incidence and trends of nosocomial infections of preterm infants in NICU and to explore their risk factors and strategies of infection control.METHODS A study was made among 1 026 hospitalized preterm infants from Jan 1992 to Dec 2004.RESULTS There were 316 times nosocomial infections in 266 preterm infants.Cumulative incidence rate for nosocomial infection was 25.9 neonates out of 100 admissions.The incidence density was 18.6 infections per 1000 patient days.The high risk factors for nosocomial infections included the parenteral nutrition,birth weight ≤1 500 g and mechanical ventilation(P<0.01).The most common infection was pneumonia(46.8%).The mortality rate of nosocomial infections was 3.8%.CONCLUSIONS It is important to identify the high risk factors for nosocomial infections of newborn infants in NICU.Reducing the duration of the parenteral nutrition and the virulence manipulation as far as possible may conduce to decrease the incidence of nosocomial infections.更多还原