【摘要】 目的探讨新疆地区汉族和维吾尔族溃疡性结肠炎(UC)患者的发病情况及临床特点的差异。方法回顾分析经临床表现结合电子结肠镜及病理学检查确诊的 UC 患者699例,其中汉族522例,维吾尔族177例,对比汉族、维吾尔族两组患者的一般资料、年龄分布、临床表现、病变范围、病情严重程度、并发症的发生等的异同。结果维吾尔族组 UC 结肠镜检出率明显高于汉族组(P<0.05)。汉族组发病年龄较维吾尔族组发病年龄大(P<0.05),且汉族组年龄分布广泛。维吾尔族组发热、里急后重及消瘦症状明显(P<0.05),且慢性持续型和急性爆发型患者明显多于汉族组(P<0.01)。汉族组与维吾尔族组全结肠炎发病率比较差异有统计学意义(24.71%vs 30.51%,P<0.05)。维吾尔族组中、重度患者明显多于汉族组(76.3%vs 47.7%,P<0.01),并发症发生率明显高于汉族组(18.6%vs 6.9%,P<0.05),UC 患者的 ANCA 阳性率61.5%明显高于汉族组35.5%(P<0.05)。结论在新疆地区,不同民族 UC 患者具有不同的发病情况和临床特点。更多还原

【Abstract】 Objective To explore the incidence and clinical characteristics of Han and Uygur pa- tients with ulcerative colitis(UC)in xinjiang.Methods Six hundred and ninty nine patients with UC from 2000 to 2006 were retrospectively reviewed.Patients were divided into 2 groups according to ethnic back- ground,including 522 Han patients and 177 Uygur patients.General data,age,clinical manifestation,le- sion range,lesion degree and complications were recorded in the 2 groups respectively.Results The detec- tion rate of UC by endoscopy in Urgur group was higher than that in Han group(P<0.05),but the onset age in Urgur group was lower than that in Han group.The age distribution in Han group was more widespread than that in Uygur group.Elderly patients in Han group were more than that in Uygur group(P<0.05).Fe- ver,tenesmus and weight loss were frequently observed in Uygur group(P<0.05).The chronic persistent and acute outbreak type in Uygur group were more than that in Han group(P<0.01).There were different in the incidence rate of pancolitis between the 2 groups(24.71% vs 30.51%,P<0.05).Moderate and se- vere UC patients in Uygur group were more than that in Han group(76.3% vs 47.7%,P<0.01).The complications in Uygur group were higher than that in Han group(18.6% vs 6.9%,P<0.05).The positive rate of ANCA in Uygur group were higher than that in Han group(61.5% vs 35.5%,P<0.05).Conclu- sion In xinjiang region,different nationality UC patients had different incidence rate and different clinical characteristics.更多还原