【摘要】 检测Graves病患者甲巯咪唑治疗前后血清细胞因子水平,发现其血清可溶性白细胞介素2受体(sIL-2R)水平治疗前与正常对照组相比显著升高,治疗后恢复正常;血清白细胞介素8(IL-8)水平下降,治疗后无明显变化,与其它指标未显示相关性。GD患者IL-1β、IL-6、肿瘤坏死因子α水平与正常对照组无差异。更多还原

【Abstract】 Serum cytokine concentrations were determined in patients with Graves’disease(GD)before and after treatment of thiamazole.Serum soluble interleukin-2 receptor(sIL-2R)level was markedly raised before treatment as compared with normal subjects and returned to normal after 3 month therapy.Serum IL-8 level was lowered in GD patients and showed no change after 3 month therapy.No relationship between IL-8 and other markers was found.Serum IL-1β,IL-6 and TNF-αlevels in GD patients showed no difference with those in normal controls.更多还原