【摘要】 目的:观察电针与药物治疗痛风性急性关节炎的疗效差异,寻找一种治疗伴肾功能不全的痛风患者的治疗方法。方法:将90例痛风性急性关节炎患者随机分为3组,电针组30例,电针三阴交、丰隆、阴陵泉等穴,每日1次,别嘌呤醇组30例,口服别嘌呤醇,每次100 mg,每日2次;丙磺舒组30例,口服丙磺舒,每次0.25 g,每日2次。观察3组对血尿酸、尿尿酸的影响及3组间疗效。结果:电针组、别嘌呤醇组、丙磺舒组治疗后和治疗前血尿酸比较,差异均有非常显著性意义(P<0.01);电针组和别嘌呤醇组治疗后组间血尿酸比较,差异无显著性意义(P>0.05)。电针组、丙磺舒组治疗后和治疗前尿尿酸比较,差异均有非常显著性意义(P<0.01);电针组和丙磺舒组治疗后组间尿尿酸比较,差异无显著性意义(P>0.05)。平均状况比较,电针组比别嘌呤醇组疗效好(56.23>43.17),别嘌呤组比丙磺舒组疗效好(43.17>37.10)。结论:电针能减少尿酸的生成和促进尿酸的排泄,治疗效果好,对肾功能无不良影响,是伴肾功能不全的痛风性急性关节炎患者有效治疗方法。更多还原

【Abstract】 Objective To compare therapeutic effects of electroacupuncture (EA) treatment and medication on acute gouty arthritis (AGA), so as to search for a therapeutic method for treatment of gout with renal insufficiency. Methods Ninety cases of AGA were randomly divided into an EA group, an allopurinol group and a probenecid group. 30 cases in each group. The EA group were treated by EA at Sanyinjiao (SP 6), Fenglong (ST 40), Yinlingquan (SP 9) , once a day; the allopurinol group by oral administration of Allopurinol, twice a day, 100 mg each time and the probenecid group by oral administration of Probenecid, twice daily, 0. 25 g each time. Contents of blood uric acid (BUA) and urinary uric acid (UUA) in each group were detected. Results In all groups, there were significant differences in BUA and UUA levels before and after treatment (P<0. 01). There was no significant difference between the EA group and the allopurinol group in blood uric acid level after treatment (P>0. 05) and there was no significant difference between the EA group and the probenecid group in the urinary uric acid level (P>0. 05). Comparison of therapeutic effects among the 3 groups indicated that the mean rank was 56. 23 in the EA group, 43. 17 in the allopurinol group and 37. 10 in the probenecid group, indicating that the therapeutic effect in the EA group was better than that in the allopurinol group, and the allopurinol group was better than that in the probenecid group. Conclusion EA can reduce the production of uric acid and promote the excretion of uric acid and has a better treatment effect. And there are no harmful effects on renal function. EA is an effective therapeutic method for treatment of gout with renal insufficiency.更多还原