【摘要】 目的:总结卵巢过度刺激综合征(OHSS)发生的各种因素。方法:以本院发生的56例轻、中、重度OHSS患者作为病例组,选择同期进行超促排卵而未发生OHSS患者为对照组,回顾性分析两组的临床资料,包括患者的年龄、体重指数、不孕原因、不孕年限、血清性激素水平、B超监测卵泡数目、超促排卵方案及促性腺激素(Gn)用量等。结果:多囊卵巢综合征或卵巢多囊样改变、采用HMG-HCG超促排卵方案、注射HCG当日E2水平和B超监测卵泡数为发生OHSS的高危因素。结论:促排卵过程中应遵循低剂量、个体化的原则,根据不同个体灵活选择促排卵方案,预防OHSS的发生。更多还原

【Abstract】 Objective:To investigate the clinical characteristics and high risk factors of ovarian hyperstimulation syndrome(OHSS).Methods:56 cases of OHSS were selected as study group and 40 cases of non-OHSS as control group.Then the OHSS group was divided into mild,moderate and severe OHSS.Clinical data of 56 OHSS patients and 40 non-OHSS were analyzed retrospectively,including patient age,body mass index,infertility causes,infertility age,serum levels of sex hormones,ultrasound monitoring follicle number,super-ovulation induction programs and gonadotropin(Gn)dosage.Results:OHSS mainly occurred after pro-ovulation treatment.Polycystic ovary syndrome or ovary polycystic,pro-ovulation treatment by using HMG-HCG,E2 levels and ultrasound for monitoring the number of follicles on the day HCG injected were the high risk factors of OHSS.Conclusion:Ovulation induction process should be followed in the low-dose and individual principle,choose ovulation induction programs flexibly in accordance with different individuals to prevent the occurrence of OHSS.更多还原