【摘要】 目的:探讨重度子痫前期终末靶器官受累特点,分析早发型和晚发型重度子痫前期终末器官受累情况与围产儿结局的关系。方法:对86例重度子痫前期患者的临床资料按起病时间以34周为界分为两组,根据器官受累情况进行分析,比较两组终末器官受累情况及围产结局。结果:86例重度子痫前期中器官受累占63.95%,早发型器官受累率80.65%,晚发型器官受累率54.55%,两组之间的器官受累率进行比较P<0.05;该文无孕产妇及新生儿死亡,有3例死胎均为胎盘早剥。结论:对早发型重度子痫前期患者,应在严密的病情观察下期待疗法至33周后适时终止妊娠,但时限最好不要超过30天为宜;对晚发型重度子痫前期患者,在病情治疗稳定之后适时终止妊娠。更多还原

【Abstract】 Objective:To analyze the clinical characteristics of end target organ damage of severe preeclampsia (S-PE) and the relationship between different patterns of end organ damage and perinatal outcomes.Methods:A prospective study was conducted in 86 pregnant women with S-PE. Early onset of S-PE was defined as those occurred at≤34 weeks and late onset of S-PE as those at>34 weeks. The clinical data were evaluated. The relations between the pattern of end organ damage and perinatal outcomes were analyzed.Results:63.95% of all 86 S-PE cases were involved in organ damage(55/86). In early onset pattern,the organ damage rate was 80.65%. In late onset pattern,the organ damage rate was 54.55%The rate of early onset group was higher than that of late onset group(P<0.05). In the study,there were no death in pregnant women and newborn. Three cases of fetal death were occurred to placental abruption.Conclusion:To early onset S-PE,should stay to 33-week-pregnant in intensive care,but shouldn’t delay more than 30 days.To late onset S-PE, should stop pregnant as soon as the condition stable.更多还原