【摘要】 目的分析CT介导经皮肺穿刺多极射频原位灭活治疗肺肿瘤的疗效。方法对92例不同病理类型的肺肿瘤综合治疗的同时行多极射频原位灭活治疗。分析治疗前后影像学、组织学变化,观察肿瘤灭活率和远期生存率。结果患者治疗中生理监测指标无明显改变,治疗后肺功能无明显影响;治疗后CT扫描肿瘤密度降低,治疗区域增强无强化。肿瘤代谢监测显示,肿瘤代谢消失,肿瘤灭活率为93.5%,远期生存率明显提高。结论多极射频原位灭活治疗肺肿瘤创伤小、效果好,安全可靠,为临床提供了一种新的安全有效的治疗方法。更多还原

【Abstract】 Objective To analyse clinical effect of CT-mediated radiofrequency in situ destruction therapy for lung cancer. Methods A CT-mediated multipole probe radiofrequency in situ destruction treatment was carried out by percutaneously for 92 cases lung cancer with different pathologic type. Destructive rate and survival rate were evaluated by imaging and fine needle biopsy. Results After RF treatment, no changes of monitored index and lung function were found and no enhancement of tumor size and density had been shown. The tumor metabolism disappeared and tumor necrosis and no tumor cell available had shown by 18F-FDP SPECT and biopsy. The in situ destruction rate of tumor was 93.5%. Long survival rate was prolonged. Conclusion CT-mediated radiofrequency in situ destruction therapy is a new, effective and minimum invasive therapy for lung cancer.更多还原