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曲美他嗪治疗老年慢性充血性心力衰竭的疗效观察

Effecfs of trimetazidine on congestive heart failure in elders

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【作者】 陈建华李友良

【Author】 CHEN Jian-hua, LI You-liang (Department of Cardiology,Xinyang Central Hospital , Xinyang 464000,China)

【机构】 河南省信阳市中心医院药剂科河南省信阳市中心医院药剂科 河南信阳464000河南信阳464000

【摘要】 目的:观察曲美他嗪对老年慢性充血性心力衰竭(CHF)的治疗效果。方法:选择CHF患者66例,随机分为2组,对照组30例,采用常规治疗方法,曲美他嗪组36例,在常规治疗的基础上加用曲美他嗪,6个月后比较NYHA心功能分级及左室射血分数,左室短轴缩短率的改善情况。结果:①两组治疗均有效,心功能明显改善。②治疗组的总有效率明显优于对照组(89%vs70%,P<0.05);心功能改善更为显著(P<0.05)。结论:曲美他嗪可改善老年CHF患者的心功能状态,增加运动耐量。

【Abstract】 Objective: To evaluate the clinical effect of trimetazidine on congestive heart failure (CHF) in elders.Methods:66 CHF patients were divied into two groups randomly. In the control group(n=30),patients were treated with commonly used drugs; In the trimetazidine group (n=36), patients were treated with commonly used drugs and trimetazidine. NYHA cardiac function grade. LVEF and FS were compared six months later. Results: Both treatments were effective for CHF in elders,and cardiac function was improved ;Effective rate of the trimetazidine group,whose cardiac function was improved significantly(P<0.05),was higher than that of the control group (89% vs 70%,P<0.05=. Conclusion:Trimetazidine is effective in the treatment on CHF in elders.

【关键词】 心力衰竭老年人充血性曲美他嗪
【Key words】 Heart failureEldersCongestiveTrimetazidine
  • 【文献出处】 中国医药导报 ,China Medical Herald , 编辑部邮箱 ,2007年34期
  • 【分类号】R541.61
  • 【被引频次】6
  • 【下载频次】15
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