【摘要】 目的:探讨主动呼吸控制(active breathing coordination,ABC)技术在肺癌精确放疗中的应用。方法:选取2006～2007年间来我科的12例肺癌患者,使用ABC技术联合三维适形放疗技术治疗,CT定位扫描时分别采集ABC和自由呼吸(free breath,FB)两套图像,计算比较两者胸壁动度、膈肌动度、大体靶区(gross tumor volume,GTV)、临床靶区(clinnical target volume,CTV)、计划靶区(planning target volume,PTV)及双肺V20、Dmean。结果:ABC状态下胸壁动度、膈肌动度、GTV、CTV、PTV及双肺V20、Dmean比FB状态下均要小,且差异有统计学意义(P<0.05)。结论:在肺癌的精确放射治疗中,ABC系统可以有效的降低呼吸运动对治疗的影响,提高放疗的精确性,减少副反应。更多还原

【Abstract】 Objective:To discuss the application in accurate radio therapy of lung cancer using the active breathing control(ABC).Methods:Choose 12 cases of lung cancer patients between 2006 and 2007,using of active breathing control in radiotherapy as a treatment technology.Each patient received computed tomography(CT) scans under two respiration:free breath(FB)and active breath-hold.Comparisons differences in the chest wall and diaphragm mobility,GTV,CTV,PTV,V20 and Dmean between ABC and FB plansy.Results:Differences in the chest wall and diaphragm mobility,GTV,CTV,PTV,V20 and Dmean between ABC and FB plans were significant(P<0.05).Conclusion:In the precise radiotherapy of lung cancer,the ABC system reduced the influence of breathing,improved the precision of the radiotherapy and reduced the toxicity.更多还原