【摘要】 [目的]评价血吸虫重复感染病人多次接受吡喹酮抗虫治疗的效果。[方法]2004~2006年,在镇江市丹徒区江滩型血吸虫病流行区,对2000~2004年接受过吡喹酮抗虫治疗2次及以上的33名血吸虫重复感染病人,采用吡喹酮60 mg/kg 2日疗法治疗,并评价其疗效。[结果]接受吡喹酮抗虫治疗6周后,粪便中均未检出血吸虫毛蚴;治疗后第24个月血清血吸虫特异性抗体阳性率由治疗前的100.00%下降至25.24%;治疗2年后B超检查肝脾肿大和肝实质损害的改善不明显。[结论]血吸虫重复感染病人多次接受吡喹酮抗虫治疗效果明显。更多还原

【Abstract】 [Objective]To access the effect of repeated praziquantel treatment on re-infected schistosomiasis patients.[Methods]33 patients re-infected by schistosomiasis,who received praziquantel treatment at least twice from 2000 to 2004,were treated with a course of qraziquantel dosage of 60 mg/kg/day for two days from 2004 to 2006 in the endemic zone,the effect was evaluated.[Results]6 weeks after the treatment,all subjects were stool-negative;in the 24th month after the treatment,the positive rate of serum specific antibodies dropped from 100% before the treatment to 25.24 %;two years after praziquantel treatment,no obvious improvement was found in B mode ultra-sound examination on liver-and-spleen swelling and hepatic parenchyma lesion.[Conclusion]Repeated praziquantel treatment is highly effective in curing patients re-infected by schistosomiasis.更多还原