【摘要】 目的探讨第三产程口服米索前列醇与肌注催产素预防产后出血的疗效比较。方法将304例自然分娩产妇随机分为两组,将第三产程第一组口服400ug米索前列醇片,第二组肌肉注射10IU催产素,第三组未予以特殊处理。观察三组产妇产后出血发生率,监测分娩前后血红蛋白浓度和药物不良反应发生率。结果289人资料齐全,三组产后出血发生率分别为8.2%、6.7%和15.4%。米索组与催产素组出血发生率和分娩前后血红蛋白浓度变化无明显差异,但均与对照组的指标有显著性差异(p<0.05)。米索组不良反应率略高于催产素组的发生。两者不良反应少且轻微。米索前列醇片用药方便。费用低,起效快,在预防产后出血方面有很广阔的应用前景。更多还原

【Abstract】 Objective to compare the efficacy of misoprostol and oxytocin in the prevention of postpartum hemorrhage. Methods divide 304 cases of natural labor into 3 groups.At the third labor stage,cases in group I will take 400ug misoprostol orally,cases in group 2 will inject 10U oxytocin,cases in group 3 will receive no treats.Observe the occurrence rate of postpartum hemorrhage,the changes of hemoglobin concentration,as well as the rates of abnormal reactions.Results the data of 289 cases are satisfactory.The hemorrhage rates of the three groups are respectively 8.2%,6.7%and 15.4%.Conclusion Use misoprostol or oxytocin in the third labor stage can obviously prevent the postpartum hemorrhage.Their abnormal effexts are rare and mild. Misoprostol is convenient,cheap and take effect quickly,which has a broad prospect in the preventin of psstpartum hemorrhage.更多还原