【摘要】 目的探讨地氟醚吸入全身麻醉时上肢短潜伏期体感诱发电位(short latency somatosensory evokedpotentials,SL-SEP)、数量化脑电图(quantitative electroencephalography,QEEG)的变化。方法选择全麻患者30例,麻醉诱导后吸入地氟醚,依次维持呼末地氟醚浓度在0.4MAC、0.7MAC、1.0MAC、1.3MAC;分别记录麻醉过程中平均动脉压(MAP)、心率(HR)、QEEG(BIS、95%SEF、MF)和SL-SEP(LP15、LN20、LN11、AMPP15-N20、AMPN11、CCT)。结果患者HR、MAP以及皮层下电位N11的变化与吸入地氟醚浓度无明显量效关系(P>0.05);而QEEG值随吸入地氟醚的呼末浓度增高而降低(P<0.05);LP15、LN20和CCT随地氟醚呼气末浓度的增加而逐渐延长(P<0.05)。结论LP15、LN20、CCT以及QEEG各参数是监测地氟醚麻醉深度的较好指标。更多还原

【Abstract】 【Objective】To evaluate the alteration of quantitative electroencephalography(QEEG) and somatosensory evoked potentials(SEP)in desflurane anesthesia.【Methods】Thirty patients undergoing general anesthesia were selected.The mean arterial blood pressure(MAP),heart rate(HR),QEEG(BIS,95%SEF,MF) and SL-SEP(LP15,LN20,LN11,AMPP15-N20,AMPN11,CCT)were respectively recorded at end-tidal concentration of desflurane 0.4MAC,0.7MAC,1.0MAC and 1.3MAC.【Results】There were no significant change of MAP,HR and P15-N20,N11 in the group(P >0.05).The latency of of P15,N20 and CCT were significantly prolonged with the increase of end-tidal concentration of desflurane(P <0.05).Increasing in the end-tidal concentration of desflurane was associated with the graded reduction of QEEG(P <0.05).【Conclusions】The P15,N20,CCT and QEEG are sensitive to monitor the depth of desflurane anesthesia.更多还原