【摘要】 目的:分析左氧氟沙星为基础的三联疗法治疗胃淋巴瘤疗效。方法:54例胃淋巴瘤的患者病理学证实淋巴瘤Ⅰ、Ⅱ期,分为抗幽门螺杆菌组(奥美拉唑,20 mg,b.i.d.,左氧氟沙星片,500 mg,b.i.d.,阿莫西林胶囊,1000 mg,b.i.d.,共服药7d,其后,口服奥美拉唑,20 mg,q.d.,7d,再抗HP治疗,共3次)及化疗组(环磷酰胺注射液,750 mg/m2,第1天,表阿霉素注射液,90 mg/m2,第1天,长春新碱注射液,1.4 mg/m2,最大量2 mg,第1天,强的松片,100 mg,第1~5天)。结果:抗幽门螺杆菌组同化疗组有效率相似(71.4%VS 76.9%),无统计学意义(P>0.05)。结论:早期胃黏膜相关淋巴组织淋巴瘤以左氧氟沙星为基础的三联疗法治疗效果较佳,不亚于化疗,是可选的一种治疗方式。更多还原

【Abstract】 Objective: To analyze curative effect that based Levofloxacin trigeminy drug therapy gastric lymphoma arising from mucosa-associated lymphoid tissue.Methods: Fifty four cases of patients confirmed histologically were all performed with pathology to diagnosis.Then divided into two groups:triple therapy anti H pylori infection(OMC: omeprazole 40 mg twice daily,amoxycillin 1 000 mg twice daily,and Levofloxacin 500 mg twice daily for one week,then omeprazole 20 mg once daily,repeatedly three times) and chemotherapy groups(Cytoxan 750 mg/m2,d1,pharmorubicin 90 mg/m2,d1,Vincristine 2 mg/m2,d1,Prednisone 100 mg,d1～5).Results: Effective power is similar between two groups,no significant difference (P>0.05).Conclusion: Therapeutic efficacy is excellent to use triple therapy based Levofloxacin in early MALT,that is no less than chemotherapy.更多还原