【摘要】 [目的]评价碘盐对改善儿童碘营养的作用和甲肿复原的影响。[方法]选择100户有8～9岁儿童的家庭免费供应合格碘盐12个月,分别于供碘盐前、供碘盐1、2、3、6、9、12个月及停止供碘盐后6个月,检测尿碘水平;供碘盐前、供碘盐12个月及停止供碘盐后6个月B超测量甲状腺容积。[结果]实验前甲状腺肿大率为36.5%,12个月后降至4.4%,停止供应碘盐6个月继续降至2.2%;供碘盐期间尿碘中位数均保持在200￣300μg/L之间,停止供应碘盐6个月后尿碘中位数下降到112.5μg/L。[结论]在中度缺碘的病区,稳定供应合格碘盐能够保证人体碘营养;供碘盐后12￣18个月可使甲状腺降到正常;与尿碘指标相比,甲状腺肿指标在判定碘缺乏上具有滞后性。更多还原

【Abstract】 [Objective]To evaluate the effects of Iodized salt intervention on the normalization of enlarged thyroid gland and iodine nutrition of children.[Methods]100 households with children aged 8-10 were selected and given free iodized salt with an iodine concentration of 20-60 mg/kg for 12 months;urinary iodine content was measured at baseline and 1,2, 3,6,9,12 and 18 months thereafter,and thyroid volume was measured by ultrasound at baseline and the 12th and 18th months.[Results]The urinary iodine median was 200-300 μg/L during given iodized salt and declined to 112.5 μg/L after stopping iodized salt;the prevalence of goiter was 35.6% at baseline and declined to less than 5% after 12 months,and to 2.2% 18 months thereafter.[Conclusion]In this sample of children with initially moderate level of IDD,receiving iodized salt with an iodine concentration of 20-60 mg/kg assure the iodine nutrition;it helps the recovery from iodine deficiency on the sizes of thyroid indicators after 12-18 months;the thyroid indicators are hysteresis compared with urinary iodine.更多还原