【摘要】 将40只雄性SD大鼠随机分为安静组8只、运动组16只、槲皮素运动组16只。以跑台训练建立动物模型,在最后一次训练时,将运动组和槲皮素运动组分别分成2个亚组:对照组和力竭运动组,每组均8只。实验期间按每天槲皮素50mg/kg体质量的剂量,于运动前3h灌胃给槲皮素运动组动物,其余组按体质量灌胃给相应量的生理盐水。通过测定力竭运动大鼠血液中血红蛋白含量、血清乳酸脱氢酶、血清丙氨酸氨基转移酶、天冬氨酸氨基转移酶活性。结果显示,服用槲皮素的大鼠在运动力竭即刻血红蛋白含量下降幅度明显小于运动力竭组,同时血清乳酸脱氢酶、血清丙氨酸氨基转移酶、天冬氨酸氨基转移酶活性的上升幅度明显降低。更多还原

【Abstract】 Totally 40 male SD rats were randomly divided into sedentary group (G1, n =8), exercise group (G2, n =16) and exercise with drug group (G3, n =16). Animal models were established by treadmill training. At the last time for training, rats in the G2 and G3 were separately divided into control group (n =8) and exhausting exercise group (n =8). Rats in the G3 were orally injected with quercetin 50 mg/kg by intragastric administration everyday at 3 hours before training, and others in the G1 and G2 were fed with the same amount of saline by gavage. Hemoglobin (Hb) content, activities of serum lactate dehydrogenase (LDH), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were determined in exhausted rats. The results showed that quercetin could remarkably restrain the decrease of Hb content and the increase of activities of ALT, AST and LDH after exhausted exercise.更多还原