Objective:To investigate the HBV DNA contents changes in the patients with hepatitis B virus in IVF-ET therapy and evaluate operation safety out of body.Methods:The HBV DNA contents in serum,in follicular fluid,in sperm washing medium,in IVF culture medium with HBV were examined by fluorescence quantitative polymerase chain reaction(FQ-PCR).Result:By FQ-PCR,HBV DNA were examined out in serum of all of 24 wives with HBsAg positive and HBeAg positive,in follicular fluid of 83.3% of them,in IVF culture medium ...
【更新日期】
2008-03-13
【分类号】
R512.6
【正文快照】
慢性乙型肝炎病毒(hepatitis B virus,HBV)感染是全世界关注的公共卫生问题,据估计全世界大约有三亿五千万HBV携带者,我国是乙肝高流行区,乙肝携带率高达10%~15%[1]。人群感染率高达60%,HBsAg携带率高达10%~15%[2]。随着现代辅助生育技术的发展,接受体外受精-胚胎移植(in vitro