【摘要】 目的探讨新生儿重症监护病房(neonatal intensive care unit,NICU)听力筛查模式及容易导致听力损失的高危因素。方法运用自动听性脑干反应(automatic auditory brainstemresponse,AABR)对353例(706耳)重症监护病房的新生儿进行初步听力筛查,随机抽样109例(218耳)正常新生儿为对照组,对比分析不同高危因素对筛查结果的影响。结果筛查NICU患儿353例(706耳),初筛未通过184例(281耳),初筛阳性率39.8%(281/706);筛查正常新生儿组109例(218耳),初筛未通过23例(27耳),初筛阳性率为12.4%(27/218),两组初筛阳性率差异有显著统计学意义(P=0.000),NICU的新生儿听力筛查初筛阳性率远高于正常新生儿。NICU新生儿不同疾病的初筛阳性率分别为:新生儿窒息46.4%,新生儿肺炎45.9%,高胆红素血症38.8%,早产儿38.1%,足月小样儿35.0%,其他34.0%。结论应用AABR技术进行听力筛查是可行的。在NICU中普及听力筛查,并对这些患儿随访、复筛,及时发现其听力损失,是提高新生儿听力损失早期诊断率的重要手段。更多还原

【Abstract】 Objective To evaluate the hearing screening model and the high-risk factors associated with congenital hearing loss for infants from neonatal intensive care unit(NICU).Methods To employ auto-auditory brainstem response(AABR)for initial hearing screenings in NICU and well baby nursery(WBN).The factors influencing the pass criteria were analyzed.Results 353 newborns of NICU and 109 newborns in WBN received AABR initial screening.Of the NICU 184 cases(281 ears)failed the screening,the referral rate was 39.8%.Of the WBN 23 cases(27ears)failed the screening,the referral rate was 12.4%(27/218).In comparison,there were significantly statistic differences between the two groups(P=0.000).The main diseases associated with those failed newborns were ranked to be asphyxia 46.4%,pneumonia 45.9%,hyperbilirubinemia 38.8%,and preterm infant 38.1% in NICU.Conclusion The application of AABR is approved to be valuable.NICU newborns should receive universal hearing screening and following-up so that early diagnosis can be made.更多还原