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人尿中美托拉宗的液相色谱-质谱研究

The Analysis of Metolazone Using LC-MS in Human Urine

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【作者】 秦旸张建丽

【Author】 QIN Yang,ZHANG Jian-li(China Doping Control Center,National Research Institute of Sports Medicine,The State Sport General Administration,Beijing 100029,China)

【机构】 国家体育总局运动医学研究所兴奋剂检测中心国家体育总局运动医学研究所兴奋剂检测中心 北京100029北京100029

【Abstract】 A sensitive and reliable procedure for analysis of metolazone in human urine by HPLC-MS was describes.The extraction recovery of liquid-liquid extraction (LLE) at various pH were studied.The detection limit of the compound was below 0.2ng at absolute amount.It is suitable for metolazone screening and confirmation in doping control.

【关键词】 MetolazoneHPLCDiureticsAnalysisHuman urine
【Key words】 MetolazoneHPLCDiureticsAnalysisHuman urine
  • 【文献出处】 分析测试学报 ,Journal of Instrumental Analysis , 编辑部邮箱 ,2007年S1期
  • 【分类号】R87
  • 【被引频次】2
  • 【下载频次】91
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