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黄芪联合强的松治疗原发性肾病综合征90例临床观察

Treatment of Astragalus Membranacenus and Prednisone in 90 Primary Nephrotic Syndrome Patients

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【作者】 龚苏飞冯曦王凤凤

【Author】 GONG Su-fei,FENG Xi,WANG Feng-feng(Dept of Nephrology,Changzhou Second people Hospital,jiangsu Changzhou 213003,China)

【机构】 常州市第二人民医院肾内科常州市第二人民医院肾内科 江苏常州213003江苏常州213003

【摘要】 目的观察黄芪治疗原发性肾病综合征的临床疗效。方法90例肾病综合征患者随机被选入泼尼松组(对照组)、丹参组(泼尼松+丹参)、黄芪组(泼尼松+黄芪),观察3组患者治疗前后尿蛋白、血浆白蛋白和血脂的变化。结果3组治疗后均见尿蛋白减少,血浆白蛋白升高和总胆固醇、甘油三酯下降,差异有统计学意义(P<0.01),但黄芪组与丹参组和对照组相比,黄芪组作用尤为明显,差异有高度统计学意义(P<0.01)。结论黄芪能减少尿蛋白量,提高血浆白蛋白,降低血脂。

【Abstract】 Objective To observe therapeutic effect of astragalus membranceus in treatment of primary nephrotic Sysdrome.Methods Ninety patients were divided into three groups at trandom: the patients in group A were treated with prednisone,in group B treated with prednisone and salvia miltiorrhiza,and in group C treated with prednisone and astragalus membranaceus.The changes in their urine.Protein,serum albumin,blood fat after the treatment were observed.Results The decrease of urine protein,increase of serum albumin and lowering in total cholesterol and triglyceride were found in the three groups(P<0.01).The patients in the group treated with astragalus membranaceus are more significant than that in the other two groups(P<0.01).Conclusion Astragalus membranaceus can decrease urine protein,increase serum albumin,and lower blood fat level.

【关键词】 黄芪肾病综合征白蛋白尿
【Key words】 astragalus membranaceusnephrotic syndromealbuminura
  • 【文献出处】 苏州大学学报(医学版) ,Suzhou University Journal of Medical Science , 编辑部邮箱 ,2007年05期
  • 【分类号】R692.3
  • 【被引频次】14
  • 【下载频次】101
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