【摘要】 目的观察缬沙坦对充血性心力衰竭(CHF)的近期疗效。方法将65例CHF患者随机分为2组,常规组治疗33例,缬沙坦组(80mg,1次/d)32例,分别于治疗前和治疗后6个月进行超声心动图监测。结果缬沙坦组32例服用缬沙坦治疗的心衰患者中,显效20例,有效8例,总有效率为87.5%。常规治疗组中显效14例,有效8例,总有效率为66.7%。2组疗效比较差异有统计学意义(P<0.05)。缬沙坦组治疗后,左室射血分数(LVEF)、左室舒张末期容积(LVEDV)、左室收缩末期容积(LVESV)、每搏量(SV)、心排血量(CO)均较常规治疗组有显著好转(P<0.05~0.01)。结论缬沙坦能有效治疗心力衰竭。更多还原

【Abstract】 Objective To observe the short-term efficacy of Valsartan on patients with congestive heart failure(CHF).Methods Sixty-five patients with CHF were randomly divided into two groups.The control group(n=33) was given routine therapy,and the treatment group(n=32) was given Valsartan(80 mg,once a day) in addition to routine therapy.Echocardiography was performed before the treatment and 6 months later.Results Twenty cases were with apparent effective and 8 cases responded slightly in the treatment group,and the total effective rate was 87.5%.In control group,there were 14 cases with apparent effective and 8 cases responded slightly,the total effective rate was 66.7%.The difference was obviously (P<0.05).LVEF,LVEDV,LVESV,SV and CO were all improved at various degrees in the treatment group compared with the control group (P<0.05～0.01).Conclusions Valsartan can effectively control heart failure.更多还原