【摘要】 目的比较原发性肝癌无水酒精注射、射频及射频综合治疗的疗效。方法对临床确诊的73例共89个病灶(<3cm,Ⅰ组)行单纯瘤内无水酒精注射治疗;124例共161个病灶(<3cm,Ⅱ组)予射频消融治疗;25例共35个病灶(>3cm,Ⅲ组)给予单纯射频消融治疗;46例共62个病灶(>3cm,Ⅳ组)于射频消融治疗之前分别进行了肝动脉化疗栓塞或瘤内无水酒精注射治疗。结果Ⅰ组:术后1个月病灶完全坏死率以及术后1,2,3和5年生存率分别为76.4%、78.8%、60.4%、52.5%和33.3%;Ⅱ组分别为91.8%、93.9%、73.2%、63.5%和46.4%;Ⅲ组分别为22.9%、47.6%、42.9%和27.3%,5年仅1例存活;Ⅳ组分别为56.5%、68.6%、46.2%、36.8%和27.3%。结论小肝癌射频消融治疗效果优于单纯无水酒精注射治疗;对>3cm肝癌应采用综合治疗。更多还原

【Abstract】 Objective To compare the therapeutic response of percutaneous ethanol injection(PEI),radiofrequency ablation(RFA) and combined therapy with RFA on hepatocellular carcinoma(HCC).Methods Seventy-three patients confirmed by pathologic and/or clinic diagnosis with 89 nodules(<3 cm,group 1) were only treated by PEI.One hundred and twenty-four patients with 161 nodules(<3 cm,group 2) were only treated by RFA.Twenty-five patients with 35 nodules(>3 cm,group 3) were only treated by RFA.Forty-six patients with 62 nodules(>3 cm,group 4) were treated by combined therapy with RFA and transcatheter arterial chemo-embolization (TACE)/or PEI.Results The complete necrosis rate of the lesions and the 1st-,2nd-,3rd-,5th-year survival rates were 76.4%,78.8%,60.4%,52.5% and 33.3% respectively in Group 1,and 91.8%,93.9%,73.2%,63.5% and 46.4% respectively in Group 2,and 22.9%,47.6%,42.9% and 27.3%,respectively and Only one patient was still alive after 5 years in Group 3,and 56.5%,68.6%,46.2%,36.8% and 27.3% respectively in Group 4.Conclusions The therapeutic response of RFA on small HCC was better than PEI.The combined therapy with RFA and TACE/or PEI should be used in large HCC.更多还原