【摘要】 目的了解肥胖症患儿尿微量清蛋白(MAU)的改变及其发生机制。方法肥胖症患儿300例及健康对照儿童100例采用免疫比浊法测定晨起MAU,同时测定血压、血糖、血脂、胰岛素水平,并进行比较。结果肥胖症患儿尤其是中、重度患儿较健康对照组MAU增高,差异显著(Pa<0.01);血压、血糖、血脂、胰岛素较健康对照组亦增高,差异显著(Pa<0.05)。结论检测MAU可早期发现肥胖造成肾损伤,其与肥胖儿高胰岛素血症、高脂血症、胰岛素抵抗、脂肪细胞因子增高有关。更多还原

【Abstract】 Objective To understand change and pathogenesis of microalbuminuria(MAU) in cases of adiposity.Method MAU were measured by immunoturbidmetric methods 300 cases of adiposity and 100 cases of nomal children in morning,meanwhile blood press,blood su-gar,blood fat,blood insulin were measured.Results MAU was higher in cases of middle and severe adiposity than normal controls.The diffe-rence was significant(Pa<0.01).Blood press,blood sugar,blood fat,blood insulin were also higher in cases of adiposity than those in normal controls.The difference was significant(Pa<0.05).Conclusions Kidney injury induced by adiposity can be found by MAU in early.It is correlated with higher blood insulin,blood fat,fat cell gene and insulin resistance.更多还原