【摘要】 目的探讨64排螺旋CT碘对比剂小剂量测试团注与增强剂量团注时,腹主动脉强化峰值到达时间的差异。方法60例心功能正常患者随机分成A、B、C组,每组20例,注射流率分别为4.5 ml/s、3.5 ml/s、4.5 ml/s,每组小剂量团注测试与增强剂量注射流率相同,A组与B组加20 ml生理盐水冲管,C组注射完对比剂后不用生理盐水冲管。另一组20例不同程度心功能不全患者作为D组,扫描方法及参数同A组。碘对比剂浓度为370 mgI/ml及采用电影模式增强扫描。测量每组小剂量团注测试及增强剂量团注扫描时肝门水平腹主动脉时间-密度曲线,比较两者到达最大强化峰值时间的差异。结果小剂量团注测试峰值到达时间变化范围,A、B、C组为19~24 s,平均分别为(20±2)s、(19±3)s、(22±3)s;D组为24~42 s,平均(28±14)s。增强剂量峰值到达时间A、B、C组变化范围为20~26 s,分别平均为(22±3)s、(21±2)s、(24±2)s;D组峰值到达时间变化范围为26~44 s,平均(32±14)s。A、B、C组小剂量测试团注与增强剂量团注时,对比剂到达肝门水平腹主动脉强化峰值时间相差约2~7 s,D组3~12 s。结论64排螺旋CT进行碘对比剂测试小剂量团注与增强剂量团注到达肝门水平腹主动脉峰值时间,不同剂量和不同注射流率之间存在差异。更多还原

【Abstract】 Objective To evaluate the arrival peak time (APT) of contrast medium to abdominal aorta at different dosages with 64-detector CT scanner.Methods Sixty cases with normal cardiac function were divided randomly into three groups(group A,B,C).The injection rate of group A,B,C was 4.5 ml/s,3.5 ml/s,4.5 ml/s respectively.A small test bolus and the enhancement dosage bolus were at the same injection rate.After the injection of contrast medium was done,20 ml saline chaser was followed in group A and B but group C.20 patients with cardiac dysfunction as group D received the same injection protocol as group A.The concentration of contrast medium was 370 mgI/ml and cine-modal was used in contrast-enhanced scanning.The time-density curve of abdominal aorta at the level of porta hepatic and APT were measured at the different group and the different dosage.Results APT of contrast medium of the small test bolus in group A,B,and C ranged from 19 s to 24 s with mean time(20±2) s,(19±3) s and(22±3) s respectively.In group D,APT ranged from 24 s to 42 s with mean time(28±14) s.APT of enhancement dosage ranged from 20 s to 26 s among group A, B,C with mean(22±3) s,(21±2) s and(24±2) s respectively.In group D,APT ranged from 26 s to 44 s,with mean time(32±14) s.The difference of APT between test bolus and enhancement dosage was 2~7 s among group A,B and C,and was 3~12 s in group D.Conclusion The APT of abdominal aorta at the level of porta hepatis between test bolus and enhancement dosage in the patients with normal cardiac function or with cardiac dysfunction is different.更多还原