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升荣胶囊联合化疗治疗晚期大肠癌疗效观察

Clinical study on advanced colorectal cancer treated by shengrong capsule combined with chemotherapy

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【作者】 相建国崔祥滨范志刚唐凤珍李曾李煜庆

【Author】 XIANG Jian-guo,CUI Xiang-bing,FAN Zhi-gang,TANG Feng-zhen,LI Zeng,LI Yu-qing Department of Oncosurgery,No.3201 Hospital of Hanzhong,Shaanxi 723000,China

【机构】 陕西省汉中3201医院陕西省汉中3201医院 陕西汉中723000陕西汉中723000

【摘要】 目的:观察升荣胶囊联合草酸铂+CF+5-FU治疗晚期大肠癌的疗效。方法:64例晚期大肠癌患者,分为治疗组(34例,升荣胶囊联合化疗)和对照组(30例,单纯化疗)观察两组疗效。结果:治疗组和对照组的临床受益率(CR+PR+SD)分别为88.2%和60.0%(P<0.05),9个月及12个月生存率分别为81.5%,74.6%和67.3%,45.8%(P<0.05)。升荣胶囊可提高细胞及体液免疫功能、杀伤肿瘤细胞,降低患者的血液高凝状态、缓解化疗药物的不良反应、改善患者的生活质量。结论:升荣胶囊联合草酸铂+CF+5-FU治疗晚期大肠癌有较好的疗效。

【Abstract】 Objective:To observe the effect of Shengrong capsule combined with L-OHP+CF+5-FU regimen in treating advanced colorectal cancer patients.Methods:Sixty four advanced colorectal cancer patients were randomly assigned to treatment group(34 patients,treated by Shengrong capsule combined with L-OHP +CF +5-FU) and control group(30 patients,treated with L-OHP + CF+5-FU regimen).The therapeutic effects of two groups were observed.Results:Clinical beneficial rates(CR+PR+SD) of treatment group and control group were 88.2% and 60.0% respectively(P<0.05),9 and 12 month survival rates were 81.5%,74.6% and 67.3%,45.8%(P<0.05).Shengrong capsule decreased blood hypercoagulability,improved cellular immune function of patients,relieved myelosuppression of chemotherapeutic agents and improved quality of life of patients.Conclusion:Shengrong capsule combined with L-OHP +CF+5-FU regimen had better effect in treatment of advanced colorectal cancer patients.

【基金】 陕西省科技厅科技研发计划项目(2005K16-G4)
  • 【文献出处】 现代肿瘤医学 ,Journal of Modern Oncology , 编辑部邮箱 ,2007年10期
  • 【分类号】R735.34
  • 【被引频次】12
  • 【下载频次】63
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