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心房颤动患者P波离散度的临床观察及胺碘酮干预

The clinicd observation of P wave dispersion and therapeutic effect of amiodarone in patients with paroxysmal atrial fibrillation

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【作者】 李震李红寇丽娜

【Author】 Li Zhen Li Hong Kou Lina The People’s Hospltal of Wuzhong(Wuzhong 751100)

【机构】 宁夏吴忠市人民医院心内科宁夏吴忠市人民医院心内科 (吴忠751100)(吴忠751100)

【摘要】 目的:探讨P波离散度能否预测阵发性心房颤动(AF)患者发生的概率及胺碘酮干预的评价。方法:选择110例冠心病(CHD)患者,其中观察组55例为CHD并AF患者;对照组55例无AF的CHD患者。测量最大P波时限(Pmax),最小P波时限(Pmin)及P波离散度(Pd),并对观察组患者给予胺碘酮干预后观察Pd变化。结果:Pmax观察组高于对照组,有显著性差异(P<0.001),Pmin观察组低于对照组(P>0.05)。观察组经胺碘酮干预后43例转为窦性心律(占78.1%),25例Pd≤40ms(占45.5%)。结论:Pd是心房颤动的独立预测指标,胺碘酮对房颤患者Pd有一定的干预作用。

【Abstract】 Objective:To investigate the association of P wave dispersion(Pd)with the occurrence rate of paroxysmal atrial fibrillation(PAF)and the efficacy with amiodarone treatment.Methods:110 patients were evaluated.55 patients with PAF served as A group and Others without PAF as B group.Electrocardiography was recorded for all the patients on admission.Then Pd,maximal and minimal P wave duration(Pmax and)were calculated.Results:Comparde with B group,the Pmax of electrocardiography of A group was obvionsly higher(P<0.001),and the Pmin was lower(P>0.05),The electrocardiography of 43 patients(78.1%)was changed into sinus rhythm and the Pd of 25 patients(45.5%)was lower than 40ms in the 55 PAF patients after treatment with amiodarone.Conclusion:Pd is a sensitive and specific predictor of PAF occurrence in patients with heart disease and can be used for the drug evaluation of anti-atrial arrhythmia.

  • 【文献出处】 陕西医学杂志 ,Shaanxi Medical Journal , 编辑部邮箱 ,2007年12期
  • 【分类号】R541.75
  • 【被引频次】2
  • 【下载频次】27
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