【摘要】 目的:用微量热法研究了白藜芦醇对白血病细胞HL-60代谢作用的热化学特征。方法:等温量热仪测定HL-60细胞在白藜芦醇作用下生长代谢的热功率输出曲线。结果:白藜芦醇在20μg/mL～80μg/mL范围内,热曲线一直处于缓慢下降状态,对该肿瘤细胞有明显抑制作用,当计量达到100μg/mL～120μg/mL时,热功率曲线值呈缓慢增加趋势,抑制效果变弱。结论:白藜芦醇对细胞HL-60代谢有明显的抑制作用,为白藜芦醇在防治肿瘤中的应用提供了可靠的信息。更多还原

【Abstract】 Objective:The micro calorimetric method was applied to the study on the thermochemical characteristics of the inhibitory action of resveratrol on the metabolism of leukaemia cell HL-60.Methods:Micro-calorimetry mensurate the export curve of the thermochemical on the cell HL-60 adding resveratrol.Results:The thermochemical curve slowly decline,and have remarkable inhibitory effect for the cell when the resveratrol’s concentration is from 20μg/mL to 80μg/mL.But when the resveratrol’s concentration is from 100μg/mL to 120μg/mL,the curve shows increase tardiness,and the inhibitory effect become weak.Conclusion:It was shown by the experimental results that resveratrol had remarkable inhibitory effect on the metabolism of the leukaemia cell HL-60,and that supply reliable information for prevention and cure of tumour(benign or malignant).更多还原