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依达拉奉治疗急性脑梗死的临床观察及其对IL-13的影响

The Effects of Edaravone on Treatment of Acute Cerebral Infarction and the Changes of Interleukin-13 in Patients’Plasma

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【作者】 郜旭吴秀萍田旻

【Author】 GAO Xu WU Xiu-ping TIAN Min (Geriatric of Department,The First Clinical College of Harbin Medical University,Harbin 150001,China)

【机构】 哈尔滨医科大学第一临床医学院干部二病房哈尔滨医科大学第一临床医学院干部二病房 黑龙江 哈尔滨 150001黑龙江 哈尔滨 150001

【摘要】 目的:观察依达拉奉对急性脑梗死的临床疗效及其对血浆白细胞介素13水平的影响。方法:60例脑梗死病例随机分为依达拉奉组及对照组,两组均采用血栓通注射剂作为基础治疗,前者加用依达拉奉静脉滴注、1日2次、共2周。用欧洲卒中评分评价临床神经功能情况,用ELISA法对血浆白细胞介素13水平进行检测。结果:依达拉奉组临床疗效明显优于对照组,治疗后与对照组相比白细胞介素13水平下降较快。结论:依达拉奉治疗急性脑梗死有效,而且安全。

【Abstract】 Objective:To observe the efficacy of Edaravone in treatment of acute cerebral infarction and its influence on the level of Interleukin-13 in patients’plasma.Methods:The sixty cases with acute cerebral infarction were divided into two groups randomly, both of which were treated with Xueshuantong injection as a basic treatment.Edaravone injection was added to the test group by intra- venous drip two times every day for two weeks.The neurological function was evaluated with ESS,and the level of Interleukin-13 in plasma was detected with ELISA Method.Results:The clinical effect in the test groups was observed significantly better than the control group,the level of Interleukin-13 in plasma in the test group decreased more rapidly than that of control group after treatment.Conclu- sion:Edaravone injection was effective and safe in treatment of acute cerebral infarction.

  • 【文献出处】 现代生物医学进展 ,Progress in Modern Biomedicine , 编辑部邮箱 ,2007年10期
  • 【分类号】R743.3
  • 【被引频次】8
  • 【下载频次】70
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