【摘要】 目的比较两种下颌前伸定位方法确定的口腔矫治器治疗阻塞性睡眠呼吸暂停低通气综合征(OS-AHS)患者的主、客观疗效,并对两种方法作出综合评价。方法采用交叉试验设计对10例男性OSAHS患者分别使用可调式口腔矫治器与计算机辅助下颌前伸定位系统(CAMRS)进行下颌前伸测定,然后患者先后分别戴用可调式口腔矫治器与根据CAMRS测定结果制作的"测定式"口腔矫治器治疗3个月;采用单因素方差分析比较两者的最适下颌前伸量以及主、客观疗效。结果可调式口腔矫治器测定的最适下颌前伸量大于CAMRS的测定值,但差异无统计学显著性意义(P>0.05);两种口腔矫治器治疗OSAHS的主、客观疗效显著,"测定式"口腔矫治器在缩短最长呼吸暂停时间、提高睡眠效率及睡眠质量方面优于可调式口腔矫治器(P<0.05)。结论两种下颌前伸定位方法各有优缺点。根据其测定结果制作的口腔矫治器对OSAHS患者均有良好的疗效。更多还原

【Abstract】 Purpose To compare and assess two mandibular repositioning methods and their efficacy in oral appliance therapy in obstructive sleep apnea/hypopnea syndrome(OSAHS).Methods A crossover-design trial was carried out on 10 male OSAHS patients.Optimal mandibular advancements were titrated through the adjustable oral appliance and the computer aided mandibular repositioning system(CAMRS) respectively.The adjustable oral appliance and the titrated oral appliance were employed to treat patients for 3 months respectively.One-way ANOVA was carried out to test the different optimal mandibular advancement and the efficacy of each oral appliance.Results The optimal mandibular advancements were larger in adjustable oral appliance than the titrated oral appliance,but with no significant difference(P>0.05).Both oral appliances showed remarkable efficacy in OSAHS patient.The titrated oral appliance had better improvement in maximum duration of apnea,sleep efficacy,and sleep qualities(P<0.05).Conclusions Each mandibular repositioning method has its advantage and disadvantage.Both oral appliances have good efficacies in the treatment for OSAHS.更多还原