【摘要】 为了探讨一过性中等负荷运动对心理应激大鼠免疫功能的影响,选用雄性SD大鼠(由西安交通大学医学院动物管理中心提供)32只,随机分为4组,即对照组(n=8)、电击组(n=8)、心理应激组(n=8)、心理应激组+一过性中等负荷30min运动组(试验组,n=8)。实验后,用放射免疫法测定血清肿瘤坏死因子α(TNF-α)和白细胞介素6(IL-6)的含量。结果显示,经过2周心理应激后,大鼠血清中TNF-α和IL-6含量显著低于对照组;一过性中等负荷运动+心理应激组血清中TNF-α、IL-6含量高于心理应激组,其中TNF-α变化具有显著性差异(P<0.05)。说明一过性中等负荷运动可导致短期心理应激大鼠血清TNF-αI、L-6浓度升高,显示其机体自然免疫功能增强。更多还原

【Abstract】 To explore the effect of instant exercise on TNF-α and IL-6 in mental stress rats.There are all together 32 male SD rats,which are provided by the Medical School of Xi`an Jiaotong University.32 male rats were divided into 4 groups randomly,control group,mental stress group,instant exercise group with 30min exercise.The concentration of Interleukin 6(IL-6) and Tumor Necrosis Factorα(TNF-α) were assayed by using radioimmunity.Results after mental stress: TNF-α and IL-6 in plasma was lower than that in control group.Instant exercise group were higher than that in mental stress group.Conclusions:instant exercise can lead to the increase of the TNF-α and IL-6 for mental stress rats.This support the upre-gulation of natural immunity.更多还原