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消脂通脉颗粒的醇提工艺研究
Study on the extraction process with alcohol of Xiaozhitongmai Granule
【摘要】 本文以乙醇为溶剂,对消脂通脉方的非挥发性成份进行了提取,以醇浸膏得率与泽泻醇B23-乙酸酯含量的综合评分为考察指标,以醇提工艺的乙醇浓度、温度、次数、时间为考察因素,用正交设计对醇提工艺条件优选,结果确定70%乙醇温浸(50℃)2次,第一次60min,第二次30min为优化工艺条件。
【Abstract】 To extract the active constituents of Xiaozhitongmai Granule with alcohol,using the yield of alcohol extractive and content of aliso B23-acetate as the detective index.Using alcohol concentration,water temperature,extraction times and extraction time as examing factors.We selected Optimum extracting conditions by The orthogonal design.which were:70% alcohol;extracting for 2 times(first time 60min,second time 30 min);water temperature was 50 ℃.
【关键词】 消脂通脉颗粒;
提取工艺;
正交设计;
【Key words】 Xiaozhitongmai Granule; extract process; The orthogonal design;
【Key words】 Xiaozhitongmai Granule; extract process; The orthogonal design;
- 【文献出处】 齐鲁药事 ,Qilu Pharmaceutical Affairs , 编辑部邮箱 ,2007年10期
- 【分类号】TQ461
- 【被引频次】1
- 【下载频次】39