【摘要】 目的探讨18F-FDG PET-CT显像对非小细胞肺癌淋巴结分期的应用价值。方法对在山东省立医院放射科行18F-FDG PET-CT检查,经病理证实为非小细胞肺癌且无远处转移的79例患者进行研究,并与同期CT对照,比较二者对纵隔淋巴结分期的价值。以病理结果为"金标准"对PET-CT和CT的结果进行统计学分析评价。结果79例患者中共有268枚淋巴结转移。对淋巴结转移的诊断敏感性、特异性、准确性,PET-CT分别为:82.84%、96.70%、89.83%;CT分别为58.58%、72.89%、65.80%。前者明显优于后者。与病理符合的肺癌N分期,PET-CT 73例,CT 58例,PET-CT的诊断准确性明显高于CT(χ2=10.05,P<0.01)。结论18F-FDG PET-CT对于非小细胞肺癌的淋巴结分期具有重要的应用价值,是一种有效的无创性影像学检查方法。更多还原

【Abstract】 Objective To investigate the clinical value of 18 F-FDG PET-CT for non-small cell lung cancer in lymph node staging.Methods 18F-FDG PET-CT(Discovery LS PET-CT in the Department of Radiology of Shandong Provincial Hospital) images of 79 patients who had undergone surgeries for histopathologically proved non-small cell lung cancers without distant metastases were analyzed.PET-CT results were compared with the CT data.Findings of both modalities were compared with pathological results and were statistically analyzed.Results There were 268 lymph node metastases in 79 patients.The sensibility,specificity and accuracy of PET-CT and CT for detecting lymphoid node metastasis were 82.84%,96.70% and 89.83% and 58.58%,72.89% and 65.80%,respectively.The former was obviously better than the latter.Overall tumor stage was correctly classified as N stage with CT in 58 patients and with PET-CT in 73 patients.Differences in the accuracy of lymphoid node staging between PET-CT and CT were significant(χ2=10.05,P<0.01). Conclusion PET-CT is a very effective imaging modality for lymph node staging of non-small cell lung cancer.更多还原