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前列腺素E1治疗老年慢性心力衰竭的临床观察

The evaluation on the effects of prostaglandin E1 in the elder chronic heart failure patients

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【作者】 卢青周晓芳钟萍张焰张新星王文艳

【Author】 Lu Qing,Zhou Xiaofang,Zhong Ping,et al.Sichuan VIP Department of Medical-science Institution Sichuan People’s Hospital,Chengdu,Sichuan 610072,China

【机构】 四川省人民医院干部医疗科四川省人民医院干部医疗科 四川成都610072四川成都610072

【摘要】 目的观察前列腺素E1治疗老年慢性心力衰竭的疗效。方法76例老年心力衰竭患者随机分为两组,实验组40例在常规治疗基础上给予前列腺素E110μg静脉注射,1次/d,每月连续14d,对照组36例予常规治疗,3个月后观察两组临床效果和心输出量变化。结果实验组临床显效62.50%,心输出量增加了38.67%,较对照组差异有统计学意义。结论前列腺素E1可以增加老年心力衰竭患者的心输出量,改善心功能,疗效好,不良反应少。

【Abstract】 Objective To observe the effect of prostaglandin E1 in the elder chronic heart failure patients.Methods 76 elder heart failure patients were divided to two groups randomly that one(the experimental group,n=40) was treated with intravenous injected Lipo-prostaglandin 10μg every day for 14 days trice within three months including conventional therapy and the others(the control group,n=36) was accepted conventional therapy,then the effect and cardiac output were observed before and after treatment.Results The rate of ecellent effect and increased cardiac output were 62.50% and 38.67% respectively in the experimental group,which showed significant difference comparing the control.Conclusion Lipo-PGE1 therapy in the elder chronic heart failure patients could increase cardiac output and improve heart function,with good effect and safety.

【关键词】 老年心力衰竭前列腺素E1
【Key words】 elderheart faihureprostaglandin E1
  • 【文献出处】 四川医学 ,Sichuan Medical Journal , 编辑部邮箱 ,2007年12期
  • 【分类号】R541.61
  • 【被引频次】2
  • 【下载频次】32
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