【摘要】 目的探讨2型糖尿病(2TDM)患者肺通气功能异常的临床意义。方法采用日本SPIROANL YEERST2300型电子肺功能仪测定肺功能各项指标:肺总量(TLC)、用力肺活量(FVC)、1秒用力呼气量(FEV1)、肺活量(VC)、最大通气量(MVV)、25%用力呼气流量(FEF25)和50%用力呼气流量(FEF50)占预计值百分比。同时测定动脉血氧分压(PaO2)、二氧化碳分压(PaCO2)和血氧饱和度(SaO2)。结果2型糖尿病组患者PaO2明显低于正常组(P<0.05),肺功能指标FVC、FEV1、FEF25和FEF50均明显低于正常组(P<0.01);2型糖尿病有合并症组FVC、FEV1、FEF25和FEF50均明显低于无合并症组(P<0.05)。结论2TDM患者存在不同程度的通气功能障碍,以阻塞性通气功能障碍为主,早期监测肺功能指标对2TDM患者肺损伤的预防和治疗可能有一定意义。更多还原

【Abstract】 Objective To research the clinical result of pulmonary funtions in patients with type-2 diabetes(2TDM). Methods The indices of TLC(%), FEV1(%), FVC(%), VC(%), MVV(%), FEF25(%), FEF50(%), PaO2、PaCO2 and SaO2 of 49 patients with type-2 diabetes(2TDM) and 38 normal subjects were monitored. Results The indices of PaO2(%), FEV1(%), FVC(%), FEF25(%), FEF50(%) in the type 2 DM patients were significantly lower than that of the control group. The indicies of FEV1(%), FVC(%),FEF25(%), FEF50(%) in type 2 DM patients with complications were significant lower than that of non-compication group. Conclusion There are various degrees of disorder in ventilation function of type 2 DM patients. Early monitoring of ventilation function of the patients would be beneficial for prevention and treatment of pulmonary injury to patients with type 2 DM.更多还原