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定量组织速度成像评价动脉粥样硬化家兔左室舒张功能的实验研究
Experiment Study on Evaluation of Left Ventricular Diastolic Function by Quantitative Tissue Velocity Imaging in Rabbits with Aherosclerosis
【摘要】 目的:应用超声定量组织速度显像(QTVI)技术评价动脉粥样硬化家兔左室舒张功能。方法:24只雄性日本大耳白兔随机分为对照组8只和实验组16只,实验组以高脂饲料饲养建立动物模型。实验组在高脂饲料饲养的8、12周测定二尖瓣环舒张早期平均峰值速度(Em)及舒张晚期平均峰值速度(Am),将Em/Am的比值进行显著性比较。结果:实验组在高脂饲料饲养的12周,Em/Am与对照组相比差异具有显著性(P<0.01)。结论:QTVI技术可以实时、客观地评价动脉粥样硬化家兔的左室功能。
【Abstract】 Objective:To evaluate the left ventricular diastolic function by quantitiative tissue velocity imaging(QTVI).Methods:24 female rabbits were randomly divided into control group(n=8) and experiment group(n=16).The animal model in experiment group was established with high fat feeds.In animals in experiment group,the peak velocity of early average diastolic E wave and late average diastolic E wave were measured at 8 and 12 week,then compared Em/Am. Results: At 12 week,the Em/Am showed significantly different between experiment group and control group(P<0.01).Conclusion: QTVI technique is feasible and objective in evaluating the left ventricular function in rabbits with atherosclerosis.
【Key words】 Atherosclerosis; Left ventricular diastolic function; Qantitiative tissue velocity imaging(QTVI);
- 【文献出处】 内蒙古医学杂志 ,Inner Mongolia Medical Journal , 编辑部邮箱 ,2007年12期
- 【分类号】R543.5
- 【被引频次】1
- 【下载频次】22