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定量组织速度成像评价动脉粥样硬化家兔左室舒张功能的实验研究

Experiment Study on Evaluation of Left Ventricular Diastolic Function by Quantitative Tissue Velocity Imaging in Rabbits with Aherosclerosis

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【作者】 陈瑶常培叶

【Author】 Chen Yao,CHANG Pei-ye(Department of Pathology,Inner Mongolia Medical College,Huhhot 010059 China)

【机构】 内蒙古医学院基础医学院病理生理教研室内蒙古医学院基础医学院病理生理教研室 内蒙古呼和浩特010059内蒙古呼和浩特010059

【摘要】 目的:应用超声定量组织速度显像(QTVI)技术评价动脉粥样硬化家兔左室舒张功能。方法:24只雄性日本大耳白兔随机分为对照组8只和实验组16只,实验组以高脂饲料饲养建立动物模型。实验组在高脂饲料饲养的8、12周测定二尖瓣环舒张早期平均峰值速度(Em)及舒张晚期平均峰值速度(Am),将Em/Am的比值进行显著性比较。结果:实验组在高脂饲料饲养的12周,Em/Am与对照组相比差异具有显著性(P<0.01)。结论:QTVI技术可以实时、客观地评价动脉粥样硬化家兔的左室功能。

【Abstract】 Objective:To evaluate the left ventricular diastolic function by quantitiative tissue velocity imaging(QTVI).Methods:24 female rabbits were randomly divided into control group(n=8) and experiment group(n=16).The animal model in experiment group was established with high fat feeds.In animals in experiment group,the peak velocity of early average diastolic E wave and late average diastolic E wave were measured at 8 and 12 week,then compared Em/Am. Results: At 12 week,the Em/Am showed significantly different between experiment group and control group(P<0.01).Conclusion: QTVI technique is feasible and objective in evaluating the left ventricular function in rabbits with atherosclerosis.

  • 【文献出处】 内蒙古医学杂志 ,Inner Mongolia Medical Journal , 编辑部邮箱 ,2007年12期
  • 【分类号】R543.5
  • 【被引频次】1
  • 【下载频次】22
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