【摘要】 目的回顾分析我院15年中心房颤动患者的病因、临床资料及药物治疗变化差异。方法将850例心房颤动患者,按时间段分成A组(374例)和B组(476例),分别对两组患者住院病历进行回顾性分析及比较。结果B组年龄>75岁患者的比例显著高于A组(P<0.05),心房颤动病因主要是高龄、冠心病、风湿性瓣膜病及高血压。与A组比较,B组患者胺碘酮的使用有下降的趋势(P<0.05),β受体阻滞剂和华法林的应用显著上升(P<0.05)。患者发生栓塞合并症显著降低(P<0.05)。结论15年间,住院的心房颤动患者治疗方案有较大的变化,但较指南的要求仍有距离。更多还原

【Abstract】 Objective To evaluate differences of general conditions,etiology,pharmaceutical therapy of patients with atrial fibrillation in 15 years in our hospital.Methods 850 patients were admitted during 1991-1996(group A) and 2001-2006(group B).The hospital records were analyzed retros pectively and compared between the 2 groups.Results The proportion of patients with advanced age was higher in group B than in group A(P<0.05).Common causes of atrial fibrillation were advanced age,coronary heart disease,rheumatic valvar disease and hypertension.Compared with group A,the use of β-blocker and warfarin significantly increased(P<0.05),but the use of amiodarone significantly decreased in group B(P<0.05).The embolism complication was significantly decreased in group B(P<0.05).Conclusions This study showed that in 15 years,the medical therapy for atrial fibrillation has changed greatly,but there is still a distance to the requirement of guidelines for the management of patients with atrial fibrillation.更多还原