【摘要】 目的探讨腺性膀胱炎电切术后应用吡柔比星膀胱内灌注化疗预防复发的疗效。方法84例病理证实的腺性膀胱炎患者,44例经尿道电切术后行吡柔比星膀胱内灌注(A组),40例仅单纯电切治疗(B组),比较两组患者术后复发率及观察吡柔比星膀胱内灌注副反应。结果随访3～54个月,平均36个月,A组6例复发,B组13例复发,两组总复发率比较差异有统计学意义(P<0.05)。吡柔比星主要副作用为尿频、尿急、尿痛等膀胱刺激症状。结论腺性膀胱炎电切术后应用吡柔比星膀胱内灌注能明显减少腺性膀胱炎电切术后复发,且副反应少,安全性较高。更多还原

【Abstract】 Objective To evaluate the therapeutic effect of intravesical instillation of pirarubicin(THP)in the cystitis glandularis after transurethral resection of the bladder tumor(TURBt).Methods Of 84 cases of pathological proven cystitis glandularis,44 cases were managed by intravesical instillation of pirarubicin after TURBt(group A),and the remaining 40 cases were not subjected to any drug after operation(group B).The recurrent rate and side effects between two groups were compared.Results After follow-up for 36 months(6～54 months),there were 6 cases and 13 cases of recurrence in group A andgroup B respectively.There was significant difference in the recurrent rate between two groups(P<0.05).The side effects of pirarubicin occurred in 3 cases of group A:urinary frequency,urgency,odynuria.Conclusion Intravesical instillation of pirarubicin after TURBt can significantly decrease the rerurrence of cystitis glandularis,and the incidence of side effects was lower.更多还原