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超声介入无水酒精量化治疗甲状腺结节的评价

Clinical Assessment of Percutaneous Thyroid Quantified Ethanol Injection in Treatment of Thyroid Nodules

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【作者】 李薇沈孝萍胡炜华胡小云冯琼

【Author】 LI Wei1a,SHEN Xiao-ping1a,HU Wei-hua2,HU Xiao-yun1b,FENG Qiong1c(1a.Department of Ultrasonic;1b.Departent of General Surgery;1c.Departent of Pathology,Second Affiliated Hospital;2.Department of Journal Editor,Medical College,Nanchang University,Nanchang 330006,China)

【机构】 南昌大学第二附属医院超声科南昌大学医学院学报编辑部南昌大学第二附属医院普外科南昌大学第二附属医院病理科 南昌330006南昌330006

【摘要】 目的:探讨超声介入注射无水酒精治疗甲状腺结节的量化方法及疗效。方法:42例甲状腺结节患者在超声引导下行无水酒精注射治疗(percutaneous ethanol injection PEI),并计算酒精注射量与弥散范围最大径、肿块大小与酒精注射量的相关系数及回归方程。结果:(1)经6个月~1年的随访,治愈者32例(76.2%),有效者7例(16.7%),无效者3例(7.1%);(2)酒精注射量与弥散范围呈正相关(r=0.775,P<0.002),甲状腺结节大小与酒精注射量的回归方程为:Y=3.02X-0.9021(式中X为结节最大径cm,Y为酒精注射量mL)。结论:通过酒精注射量与弥散范围相关关系研究导出的甲状腺结节直径与酒精注射量的回归方程经临床应用与随访观察,疗效较好,可作为行PEI时酒精注射量的计算方法。

【Abstract】 Objective:To probe the method of percutaneous ethanol injection(PEI) in treatment of thyroid nodules.Methods: In 42 patients with autonomous thyroid nodules were treated by ultrasound guided PEI.The interrelated coefficience of the quantity of alcohol injection into the nodules and the diameters of spreading areas of the alcohol on the screen were measured.The regressive quantity of the diameters of the nodules and the quantity of alcohol were calculated.Results:(1)After three months to one year follow-up,32 cases(76.2%) were healed,7(76.2%) recovered,and 3(16.7%) no effect.(2)The quantity of alcohol and the alcohol spreading area was markedly positive interrelated(r=0.775,P<0.002).The regressive equation of the diameters of the nodules and the quantity of alcohol was Y=3.02X-0.9021(X was the alcohol diameter,the unit was cm.Y was the alcohol quantity,the unit was ml).Conclusion: Thyroid nodules are cured by PEI with the quantified alcohol calculated by the regressive quantity of the diameters of the nodules and the quantified alcohol inferred from the interrelationship between the quantity of alcohol and the diameter of spreading area of the alcohol.

  • 【文献出处】 实用临床医学 ,Practical Clinical Medicine , 编辑部邮箱 ,2007年08期
  • 【分类号】R581
  • 【被引频次】3
  • 【下载频次】149
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