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结外鼻型NK/T细胞淋巴瘤

A case report of extranodal nasal-type NK/T cell lymphoma

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【作者】 潘卫利郑福兆付兵初罗静

【Author】 PAN Wei-li, ZHENG Fu-zhao, FU Bing-chu, LUO Jing (Department of Dermatology, Zhejiang Provincial People’s Hospital, Hangzhou 310014, China)

【机构】 浙江省人民医院皮肤科浙江省人民医院皮肤科 浙江杭州310014浙江杭州310014

【摘要】 报告1例结外鼻型NK/T细胞淋巴瘤。患者女,67岁。面部反复出现红斑、肿胀10年,头痛1周。体格检查:T37.6℃,左额部大片暗红色浸润性斑块,表面光滑,无鳞屑,有结痂脱落痕迹。斑块边界欠清,鼻根部肿胀。鼻腔内有较多痂皮及脓性分泌物,左鼻腔内充满坏死组织及新生物。免疫组化染色:LCA、CD2、CD3、D45RO、CD56、粒酶B均(+)。CD4、CD8、CD20均(-)。组织病理诊断:结外鼻型NK/T细胞淋巴瘤。

【Abstract】 A case of extranodal nasal-type NK/T cell lymphoma with skin involvement is reported. A 67-year-old female had erythema and swelling on her face for 10 years. She experienced headache for 1 week. Physical examination revealed dark erythematous plaque on her left forehead. The tumor had smooth surface with residue of crust, but no scales, and without defined boundary. The root of nose was swollen. There were crusts and purulent secretion in the nasal cavity, with left side filled with tumor and necrotic tissue. Immuno-histochemistry staining: LCA(+), CD2(+), CD3(+), CD4(-),CD8(-),CD20(-), CD45RO(+), CD56(+), Granzyme B(+). The pathological diagnosis was nasal-type NK/T cell lymphoma.

【关键词】 淋巴瘤,NK/T细胞鼻部
【Key words】 lymphoma, NK/T cellnasal
  • 【文献出处】 临床皮肤科杂志 ,Journal of Clinical Dermatology , 编辑部邮箱 ,2007年08期
  • 【分类号】R733.1
  • 【被引频次】1
  • 【下载频次】162
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