【摘要】 目的观察老年患者术中回收式自体输血前后凝血参数的变化。方法24例择期手术的老年患者随机分为回收式自体输血组(观察组)或异体输血组(对照组)。观察组12例,回输经血液回收仪洗涤处理的自体血;对照组12例,输异体浓缩红细胞。分别取术前、输血前和输血后的静脉血,测定血常规、凝血酶原时间(PT)、活化的部分凝血活酶时间(APTT),同时Sonoclot仪测定血凝曲线的各项指标。结果两组术前、输血前和输血后Hb、血小板计数(Plt)、纤维蛋白原(FIB)、APTT及PT水平变化趋势相似。观察组的血块凝结速率(CR)值自体血回输前与手术前相比变化明显(P<0.05),但与对照组比差异无统计学意义。两组间Sonoclot仪其他各项指标在各测定点差异也无统计学意义。结论术中回收式自体输血与异体输血相比对老年人凝血功能的影响差异无统计学意义。更多还原

【Abstract】 Objective To evaluate the changes of coagulation function in the ederly patients after reinfusion of autologous scavenged red blood cells.Methods Twenty-four ederly patients undergoing elective spinal operation were randomly divided into two groups .Twelve patients in study group received autologous blood retransfusion,and the other twelve patients in control group were given homologous blood transfusion .Coagulation functions were monitored.Results The similar trends of dynamic changes were observed in Hb,FIB,Plt,PT and APTT after blood transfusion compared with those before in the two groups.There were no significant differences in Sonoclot parameters including clot rate between the two groups.Conclusion Rinfusion of autologous scavenged red blood cells has no significant effects on blood coagulation functions compared with homologous blood transfusion in the elderly.更多还原