【摘要】 目的:了解长期服用抗精神病药的慢性精神分裂症住院患者迟发性运动障碍(TD)的预后。方法:对以往诊断为TD的54例住院患者TD症状进行6年随访。结果:42.6%患者TD症状改善,35.2%患者症状不变,22.2%患者症状恶化。服用新型非典型抗精神病药者TD症状改善较明显。患者的年龄、性别、目前药物剂量、药物剂量的改变、首次用药年龄、累计服药时间及总病程对TD症状的改善无影响。结论:长期用药患者TD症状仍可有所改善,新型非典型抗精神病药物可能改善TD症状。更多还原

【Abstract】 Objective:To understand the prognosis of tardive dyskinesia(TD)in chronic inpatients with schizophrenia taking antipsychotics chronically.Method:54 inpatients diagnosed with TD previously were follow-up for 6 years.Results:42.6% patients had an alleviation in symptoms of tardive dyskinesia,with 35.2% unchanged and 22.2% exacerbated,which were improved significantly in the patients taking atypical antipsychotics.The factors,such as patient’s age,gender,present drug-taking dosage,dosage change,age of first drug-taking,total time of drug-taking and total illness course,had no influence on the improvement of TD.Conclusion:Symptoms of tardive dyskinesia can still be improved in patients taking antipsychotics chronically.Atypical antipsychotics may ease the symptoms of tardive dyskinesia.更多还原