【摘要】 目的探讨环孢霉素A诱发可逆性后部白质脑病综合征(PRLS)的MRI表现。资料与方法回顾性分析1例PRLS的临床资料和MRI表现并复习文献。结果MRI显示PRLS以顶枕叶为主的皮层及皮层下白质病变,病变多呈双侧对称性分布,偶可累及双侧颞叶后部及额叶,T2WI和液体衰减翻转恢复序列(FLAIR)对病变的显示有独特的作用,扩散加权成像(DWI)能够确定PRLS的临床分期。结论PRLS在MRI上具有特征性。MRI表现结合临床资料,对PRLS多能作出正确的诊断。更多还原

【Abstract】 Objective To investigate the MRI features of posterior reversible leukoencephalopathy syndrome (PRLS)induced by cyclosporine A. Materials and Methods The clinic data and MRI images of 1 case with PRLS were retrospectively analyzed and related reports were reviewed. Results The lesions mainly located in the cortex and subcortical white matter of parietal and occipital lobes and distributed symmetrically, and lesions occasionally spread to the posterior part of the bilateral temporal lobes and frontal lobe. The T2WI and the FLAIR sequences had a special role in revealing the lesions, and the DWI sequence was able to determine the clinical stages of PRLS. Conclusion The MRI characteristics of PRLS are typical and the combination of MR imaging with clinical data can make a correct diagnosis.更多还原