【摘要】 目的探讨肺癌患者血清中鳞状细胞癌抗原(SCC-Ag)表达的临床意义。方法用酶联免疫吸附法分析90例确诊的肺癌患者及30例肺良性疾病对照组患者血清中SCC-Ag水平,并结合临床资料分析该指标的临床意义。结果肺癌组患者血清中SCC-Ag水平明显高于肺良性疾病对照组(P<0.05);临床分期越晚,SCC-Ag水平越高,Ⅳ期患者血清中SCC-Ag水平与Ⅰ、Ⅱ、Ⅲ期患者相比有统计学差异(P<0.05);不同病理类型肺癌患者血清中SCC-Ag阳性率以鳞癌最高为68.5%。结论SCC-Ag可作为肺癌诊断、分型及判断预后的指标。更多还原

【Abstract】 Objective To investigate the clinical significant of the SCC-Ag expression in the serum of the patient with lung cancer.Methods Combining the clinical data,the level of SCC-Ag in 90 cases who wee diagnosed as lung cancer and 30 cases diagnosed as lung benign lesion(Control Group)of elisa were analyzed.Results The level of SCC-Ag in the lung cancer was obviously higher than that in the control group.Furthermore,as the clinical stage progressed,the level of the SCC-Ag expression increased.There were significant differences in the SCC-Ag expression between Stage Ⅳ and StageⅠ,and between StageⅡ,and stageⅢ(P<0.05).Among the different pathological types of lung cancer,it was the SqCa that had the highest positive rate of the SCC-Ag(68.5%).Conclusion SCC-Ag was the valuable index in diagnosing,histological typing,and prognosis assessment of lung cancer.更多还原