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系统性淋巴结清扫在非小细胞肺癌手术中的应用
Application of Systematic Lymphadenectomy in Non-small Cell Lung Cancer Operation
【摘要】 目的探讨非小细胞肺癌(NSCLC)手术中系统性淋巴结清扫的意义和术后的效果.方法收集Ⅰ~Ⅲa的NSCLC 144例,分成研究组和对照组.研究组肺切除时行系统纵隔淋巴清扫术,对照组肺切除时仅行肺门淋巴结清扫术,纵隔淋巴结肉眼怀疑转移者则行该淋巴结摘除术.分析淋巴结清除总数﹑淋巴结转移数﹑淋巴结转移率﹑手术并发症,术后进行随访.结果研究组共清除淋巴结657枚,转移淋巴结402枚,转移率为61.2%(402/657);对照组共清除淋巴结275枚,转移淋巴结215枚,转移率为78.1%(215/275).两组术后并发症无明显差异.术后随访,研究组仅1例转移,对照组中2例复发,4例转移.结论非小细胞肺癌手术中系统性淋巴结清扫能够减少术后的复发率和转移率,提高病人长期生存率.
【Abstract】 Objective To explore the significance and effects of systematic lymphadenectomy in non-small cell lung cancer operation.Methods Ⅰ~Ⅲa 144 case operable eligible,uses with NSCLC were divided to a systematic lymphadenectomy group(research) and a conventional lymph node dissection group(control).Analyze total number of dissected lymph node,number of metastatic lymph nodes,metastasis ratio of lymph node,postoperative complication,postoperative follow-up visit.Result The research group eliminate total number of lymph nodes were 657,metastatic lymph nodes were 402,metastastic ratio of lymphy nodes was 61.2 %(402/657).The control group eliminate total number of lymphy nodes were 275,metastaic lymphy nodes were 215,metastasis ratio of lymph nodes was 78.1 %(215/275).Postoperative compication have no obviously difference between two groups.Postoperative follow-up visit indicated that had one case metastasis in research group and four cases metastasis and two cases recurrence in control group.Conclusion Application of systematic lymphadenectomy in Non-small cell Lung cancer operation can decrease postoperative ratio of recurrence and postoperative ratio of metastasis and can raise long-term survival ratio of patient.
【Key words】 Non-small cell lung cancer; Lung cancer operation; Systematic lymphadenectomy;
- 【文献出处】 昆明医学院学报 ,Journal of Kunming Medical College , 编辑部邮箱 ,2007年06期
- 【分类号】R734.2
- 【被引频次】5
- 【下载频次】113