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硫喷妥钠联合机械通气救治癫痫持续状态的临床探讨
Clinical Study of Thiopental Combined with Artificial Ventilation for Rescuing Status Epilepticus
【摘要】 【目的】探讨癫痫持续状态的治疗方法,评价硫喷妥钠联合机械通气抢救癫痫持续状态的疗效。【方法】45例患者依据临床特征、脑电图确诊为癫痫持续状态,入院后立即行硫喷妥钠1.0 g加入0.9%氯化钠溶液中,使用微量泵3~8 mg/min静滴。同时采用气管插管机械通气,根据血气分析合理选择呼吸模式和调节呼吸机参数,加强呼吸道管理。【结果】45例于5~30 min内抽搐全部控制,3~24 h内意识转清,生命体征、血气分析均恢复正常。【结论】使用硫喷妥钠联合机械通气控制癫痫持续状态快速、高效、安全。
【Abstract】 【Objective】To evaluate the effect of thiopental combined with artificial ventilation on status epilepticus,and explore an effective therapy for status epilepticus.【Methods】 Forty five cases of status epilepticus were finally comfirmed by clinical examination and eletroencepalograph(EEG).Thiopental(5%) was intravenously injected via microinfusion pump proceeded by trachea intubation and artificial ventilation immediately after admission.The optimal ventilation patterns and parameters were set up guided by blood gas analysis.【Results】 The seizure of all 45 cases were relieved successfully within 5~30min after treatment.All patients recovered consciousness within 24 hours with normal vital signs and blood gas.【Conclusion】 Thiopental combined with artificial ventilation is fast,effective and safe in the treatment of status epilepticus.
【Key words】 status epilepticus/TH; thiopental/TU; respiration,artificial;
- 【文献出处】 医学临床研究 ,Journal of Clinical Research , 编辑部邮箱 ,2007年11期
- 【分类号】R742.1
- 【被引频次】1
- 【下载频次】31