【摘要】 目的:观察交联纤维蛋白二聚体(D-D)含量,探讨凝血及纤溶机能紊乱与慢性阻塞性肺病(COPD)发生发展间的关系及临床意义。方法:选择我院ICU及呼吸科住院的慢性阻塞性肺病急性发作期患者25例,缓解期的慢性阻塞性肺病患者24例,及28例健康体检者,空腹安静时抽取肘静脉血,采用酶联免疫吸附双抗体夹心法测定交联纤维蛋白二聚体(D-D)含量。结果:以均数±标准差(x±sd)表示,t检验进行统计学处理。结论:COPD患者急性发作期体内存在凝血及纤溶系统平衡失调,处于血栓前状态。因此,D-D的检测对于COPD的发展及治疗具有重要的临床意义。更多还原

【Abstract】 Objective: To observe the content of d-dimer,investigate their relations between the disorder of hemoglutintion filament dissolve function and COPD’s development,progression,clinical significance.Method: We collected 25 acute attack hospitized patients in ICU and in respiratory wards.24 alleviated patients and 28 normal health physical examined patients.Adopted blood in elbow vein when they were peaceful and on an empty stomach.Examinated the content of d-dimer with ELISA method.The result is expressed by x+sd,T-test was statistically analyzed.Result: There is balance disorder between hemoglutintion and filament dissolve system among the acute attacked COPD patients,It is prethrombosis state,therefore,the test of d-dimer has the vital clinical significance to the development and treatment of COPD.更多还原