【摘要】 目的对利可君含量的测定条件进行优化。方法在保证分离效果的前提下以提高信噪比的大小来优化流动相。结果乙腈-磷酸盐缓冲液(PBS,pH6.8)-冰醋酸-磷酸(38∶62∶0.12∶0.07)为最佳流动相条件。结论本色谱条件显著改善了原分析方法的信噪比,实现对利可君准确、快速、经济实用的分析,为质量标准的修订提供可行的依据。更多还原

【Abstract】 OBJECTIVE To improve and estabilish a HPLC assay of leucogen.METHODS A HPLC method was improved by changing the contents of mobile phase.RESULTS Acetonitrile-phosphate buffered soulution(PBS,pH6.8)-glacial acetic acid-phosophoric acid(38∶62∶0.12∶0.07)was the best mobile phase condition.CONCLUSION The established method was accurate,reliable and economical.更多还原