【摘要】 建立了细辛脑中相关杂质的气相色谱快速分析方法。色谱柱为HP-1石英毛细管柱(30 m×0.53 mmi.d.,1.5μm),检测器为FID氢火焰离子化检测器,柱温185℃。能够明确的测定细辛脑中3种物质:β-细辛脑、2,4,5-三甲氧基苯甲醛、1-(2,4,5-三甲氧基苯基)-1-丙醇。细辛脑进样量在0.010～10.140μg范围内线性关系良好,r=0.9995,方法平均回收率为99.5%(n=9),细辛脑的检出限为0.304 ng。该方法对细辛脑合成工艺优化和样品的质量控制均具有指导作用。更多还原

【Abstract】 A capillary gas chromatographic method for analyzing asarone and its related substances was established.The sample was analyzed on a HP-1 capillary column(30 m×0.530 mm i.d.,1.5 μm),the detector was flame ionization detector(FID) and the column temperature was set at 185 ℃.The method can be used for the determination of three compounds: β-asarone,2,4,5-trimethoxybenzaldehyde,1-(2,4,5-trimethoxyphenyl)-1-propanol.The linear range for the detection of asarone was 0.010～10.140 μg(r=0.9995),the average recovery of the method was 99.5%(n=9),and the detection limit of asarone was 0.304 ng.The established GC method is accuracy and sensible for asarone determination.It will play an important role in quality control of synthetic process.更多还原