【摘要】 目的:应用标准测量法对磁共振血管成像大脑中动脉狭窄程度进行标准化的测量研究。方法:34例患者中男23例、女11例,平均年龄62.5岁。应用标准测量法对其中46条经过TCD确诊为中、重度狭窄的大脑中动脉M1段的MRA血管狭窄率进行测量,计算公式为:狭窄率=[1-(狭窄动脉直径÷正常动脉直径)]×100%;狭窄动脉直径为大脑中动脉M1段最狭窄处管腔横径,正常动脉直径的测量遵循以下原则:第1选择测量大脑中动脉M1段狭窄处近心端正常动脉血管的直径;如果近心端的动脉血管也有管腔的不规则狭窄采用第2选择测量大脑中动脉M1段狭窄处远心端正常动脉血管的直径;如果近心端和远心端的大脑中动脉M1段均有不规则狭窄则采用第3种选择测量大脑中动脉的供血动脉颈内动脉的血管直径。结果:对正常血管的选择和狭窄率的测量结果经2个独立样本的t检验差异都无显著性意义(P>0.05);MRA测量结果平均值与TCD测量Vs值经一元线性相关与回归分析结果R2=0.55。结论:标准测量法应用于MRA血管狭窄率的测量可以得到较好的一致性,如果进一步研究可以成为计算MRA血管狭窄率标准方法。更多还原

【Abstract】 Objective:Applied a standardized method for measuring the stenosis of middle cerebral artery by MRA.Methods:46 stenosis M1 of middle cerebral arteries of 34 patients were diagnosing by TCD,2 radiologists measured the stenosis on MRA by a standardized method as follows:rate of stenosis=[1-(Dstenosis/Dnormal)]×100%,where the D stenosis=the diameter of the artery M1 at the site of the most severe stenosis and Dnormal=the diameter of the proximal normal artery,if the proximal segment was diseased,contiguous sites were chosen to measure Dnormal,and distal artery (second choice),feeding artery (third choice).Results:Between 2 radiologists the choice of Dnormal and percent stenosis measuring result were analysis by two independent sample t-test,P>0.05.The average of percent stenosis and the Vs of TCD were analysis by liner regression,and the coefficient of determination R2=0.55.Conclusion:The method shows good intraobserver agreements for measurement of middle cerebral on MRA.If validated in subsequent studies,this method may serve as a standard for the measurement of percent stenosis of an intracranial artery by MRA.更多还原