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甲强龙冲击疗法联合高压氧治疗鼻咽癌放疗后放射性脑病的临床疗效观察
Clinical effects of methylprednisolone pulse therapy combined with hyperbaric oxygen for radiation encephalopathy after radiotherapy of nasopharyngeal carcinoma
【摘要】 目的探讨甲强龙冲击疗法联合高压氧治疗鼻咽癌放疗后放射性脑病的临床疗效,提高对鼻咽癌放疗后放射性脑病防治的认识。方法选取符合入选标准的研究对象60例,分为观察组和对照组。观察组30例使用甲强龙冲击疗法联合高压氧治疗,对照组30例使用传统药物治疗,观察两组研究对象的临床疗效。结果观察组的临床疗效与对照组比较差异有显著性意义(P<0.05)。结论甲强龙冲击疗法联合高压氧治疗鼻咽癌放疗后放射性脑病的临床疗效优于传统药物治疗。鼻咽癌放疗后一旦出现放射性脑病,应做到早期诊断、早期治疗,及时运用甲强龙冲击疗法联合高压氧的积极治疗措施。
【Abstract】 Objective To study the clinical effects of methylprednisolone pulse therapy combined with hyperbaric oxygen for radiation encephalopathy after radiotherapy of nasopharyngeal carcinoma,and to enhance the knowledge of preventing and treating the radiation encephalopathy after radiotherapy ofnasopharyngeal carcinoma.Methods In 60 examples meeting the selection criteria,30 as the observation group were treated with methylprednisolone pulse therapy combined with hyperbaric oxygen treatment,and the other 30 as the control group were treated with conventional medicine treatment.The clinical therapeutic outcomes were observed and compared in the 2 groups.Results The therapeutic outcomes were better in the observation group than that in the control group obviously (P<0.05).Conclusion Methylprednisolone pulse therapy combined with hyperbaric oxygen is superior to the conventional medicine treatment in the treatment of radiation encephalopathy after radiotherapy of nasopharyngeal carcinoma.Once radiation encephalopathy appears in patients with nasopharyngeal carcinoma after radiotherapy,the early diagnosis,the early treatment,and the combined therapy of methylprednisolone pulse therapy and hyperbaric oxygen should be taken for the guarantee of better prognosis.
【Key words】 Methlyprednisolone pulse therapy; Hyperbaric oxygen; Nasopharyngeal carcinoma; Radiotherapy; Radiation encephalopathy;
- 【文献出处】 中华神经医学杂志 ,Chinese Journal of Neuromedicine , 编辑部邮箱 ,2007年04期
- 【分类号】R739.63;R818
- 【被引频次】11
- 【下载频次】19