【摘要】 目的:探讨间歇性过量运动对大鼠机体健康的影响及其生物化学机理。方法:45只Wistar大鼠随机分为3组(每组15只):安静对照组(C)、一般运动组(NE,在动物跑台15m.min-1运动,每周运动5d,每天运动时间30min×2,间歇10min)和过量运动组(OE,每周连续2天进行2次过量运动,速度为20m.min-1,每次运动时间100min×2,间歇10min)。3组大鼠运动8周后处死,对大鼠血液中血红蛋白、红细胞压积等15项生化指标进行检测。结果:与C组和NE组比较,OE组大鼠血液中磷酸肌酸激酶(CK)、乳酸脱氢酶(LDH)、丙氨酸转氨酶(ALT)明显升高(P<0.05或P<0.01),血红蛋白(HGB)、IgG、总蛋白(TP)、白蛋白(ALB)明显降低(P<0.05或P<0.01)。与C组比较NE组WBC、RBC、HDL、TP、IgG明显升高(P<0.05或P<0.01),LDL明显降低(P<0.01)。结论:间歇性过量运动对大鼠血液中的某些生化指标产生不良的影响。更多还原

【Abstract】 Objective To study the influence of interim overload exercise on health and it’s biochemical mechanism.Methods 45 Wistar rats were randomly divided to three groups(n=15):no exercises group(control,C),normal exercise group(NE,the rats ran in the animal running machines at 15 m·min-1for 5 d in one week,exercise time was 30 min×2,and rested for 10 min after ran for 30 min),overload exercise group(OE,the rats exercised 2 bouts,2 d in consecutive in one week,exercise time was 100 min×2,and they rested for 10 min after ran for 100 min).After training for 8 weeks,the rats in three groups were sacrificed and 15 biochemical indexes in blood of rats were determined.Results Compared with C and NE groups,CK,LDH,and ALT increased obviously(P<0.05 or P<0.01);HGB,IgG,TB and ALB decreased(P<0.05 or P<0.01)in OE group;compared with C group,WBC,RBC,HDL,TP and IgG increased obviously(P<0.05 or P<0.01),and LDL decreased(P<0.01)in NE group.Conclusion Interim overload exercise has some bad influence on biochemical indexes in blood of rats.更多还原